Microwave-assisted synthesis and evaluation of N-substituted thiazolidine-2, 4-dione derivatives as antimicrobial agents

نویسندگان

  • Santosh L. Gaonkar
  • Nitinkumar S. Shetty
  • Hiroki Shimizu
چکیده

A series of N-substituted thiazolidine-2,4-dione derivatives bearing potentially bioactive substituents were synthesized by microwave irradiation method. Structural elucidation was accomplished by 1H NMR, 13C NMR, IR, Mass and elemental analyses. The synthesized compounds were evaluated for antimicrobial activities. Among the compounds studied, compounds 4i and 4d showed potent antimicrobial activities.

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تاریخ انتشار 2015